產(chǎn)品名: ABT-199

Cas No.: 1257044-40-8

分子量: 868.44

分子式: C45H50ClN7O7S

別名: ABT199, ABT 199, GDC0199, GDC-0199

化學(xué)名:
4-[4-[[2-（4-chlorophenyl）-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1

 

 

產(chǎn)品名: ABT-199   

 

Cas No.: 1257044-40-8

 

分子量:  868.44

 

 分子式:  C45H50ClN7O7S

 

 別名: ABT199, ABT 199, GDC0199, GDC-0199  

 

化學(xué)名:  

4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide

溶解性: >43.4mg/mL in DMSO

儲(chǔ)存條件: Store at -20°C  

ABT-199是通過(guò)基于結(jié)構(gòu)的逆向過(guò)程而研發(fā)的，是一種新型的特異性BCL-2抑制劑，具有低濃度的親和力