L-Homopropargylglycine,HPG,炔標(biāo)記蛋氨酸，蛋氨酸，包含一個(gè)非常小的修飾氨基酸模擬，特別是疊氮基團(tuán)可以飼養(yǎng)細(xì)胞和摻入蛋白質(zhì)蛋白質(zhì)的合成過程中。檢測(cè)采用化學(xué)選擇性結(jié)扎或“點(diǎn)擊"的疊氮化物和炔基或環(huán)辛炔的反應(yīng)。疊氮基改性蛋白檢測(cè)用熒光或生物素炔炔。

L-Homopropargylglycine,HPG,炔標(biāo)記蛋氨酸

L-Homopropargylglycine

L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety that can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or &lduo;click &rduo; reaction between an azide and an alkyne or cyclooctyne. The alkyne-modified protein is detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and patible with downstream LC-MS⁄MS and MALDI MS analysis.

Molecular weight	163.60 (HCl salt)
Chemical position	C6H10ClNO2
CAS	98891-36-2
Solubility	Water, DMSO, DMF
Purity	>95% (H NMR)
Appearance	White crystalline
Storage conditions	-20C
Shipping conditions	Ambient temperature

L-Homopropargylglycine,HPG,炔標(biāo)記蛋氨酸

公司：西安凱新生物科技有限公司

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