磁共振兼容型大鼠小鼠監(jiān)護(hù)儀,是starr公司為MRI磁共振環(huán)境下大鼠、小鼠的生命體征檢測(cè)專(zhuān)門(mén)開(kāi)發(fā)的設(shè)備。

可以在MRI環(huán)境下測(cè)量小動(dòng)物(幼鼠小鼠大鼠豚鼠兔等)的血氧飽和度脈搏頻率呼吸頻率脈搏幅度呼吸幅度；

所有測(cè)量都是通過(guò)一個(gè)的感應(yīng)器；

主要功能

· 無(wú)磁探頭適合核磁環(huán)境中監(jiān)測(cè)動(dòng)物的生命體征；

· 監(jiān)測(cè)和記錄多種心肺功能參數(shù)動(dòng)脈血氧飽和度脈搏脈搏幅度呼吸頻率呼吸幅度

· 可輸出模擬數(shù)據(jù)

所有測(cè)量都是通過(guò)一個(gè)的感應(yīng)器完成準(zhǔn)確、方便、高效。

型號(hào)MouseOx     正在對(duì)麻醉狀態(tài)下的小鼠進(jìn)行測(cè)試

有多種探頭可供選擇

· 根據(jù)實(shí)驗(yàn)需求可選擇大鼠型探頭、小鼠型探頭；

· 根據(jù)動(dòng)物狀態(tài)可選擇清醒活動(dòng)狀態(tài)連續(xù)測(cè)量和麻醉（或手術(shù)）狀態(tài)測(cè)量探頭；

· 根據(jù)動(dòng)物數(shù)量有多通道適配器可供選擇同時(shí)檢測(cè)多只動(dòng)物的生命體征；

· 根據(jù)使用環(huán)境可選擇核磁環(huán)境適用的無(wú)磁探頭；

經(jīng)過(guò)驗(yàn)證的準(zhǔn)確度:

使用有創(chuàng)血?dú)獠蓸訙y(cè)量結(jié)果與 MouseOx 測(cè)量結(jié)果的比較 對(duì)比表明 兩者具有很好的線性關(guān)系。

脈搏、血氧、呼吸等心肺監(jiān)測(cè)參數(shù):

· 脈波頻率在90到900BPM范圍內(nèi)監(jiān)測(cè) (每分鐘心跳, Beat per minutes, BPM)

· 血氧飽和度監(jiān)測(cè)范圍0% 到99% 動(dòng)脈血氧飽和度；

· 血氧飽和度監(jiān)測(cè)誤差<1.5% 橫跨整個(gè)監(jiān)測(cè)范圍；

· 血氧飽和度監(jiān)測(cè)反應(yīng)時(shí)間實(shí)時(shí)報(bào)告動(dòng)脈血氧飽和度, 在每次心跳以后0.72秒屏幕刷新；

· 呼吸頻率監(jiān)測(cè)范圍每分鐘 25到450 次；

· 監(jiān)測(cè)反應(yīng)時(shí)間呼吸率每1.7秒向用戶(hù)報(bào)告, 移動(dòng)報(bào)告的值是10次呼吸的的平均數(shù)；

· 傷監(jiān)測(cè)脈搏充盈度以估量血流量的變化；

· 脈搏監(jiān)測(cè)范圍內(nèi)徑0到800微米的徽小血管；

· 監(jiān)測(cè)誤差< 2.4%橫跨整個(gè)監(jiān)測(cè)范圍；

· 監(jiān)測(cè)反應(yīng)時(shí)間脈搏充盈度實(shí)時(shí)向用戶(hù)報(bào)告, 在每次心跳以后,0.72秒屏幕刷新刷新屏幕顯示被測(cè)量的所有脈搏充盈度；

· 傷監(jiān)測(cè)動(dòng)物呼吸幅度的變化；

· 呼吸幅度監(jiān)測(cè)范圍每分鐘25到450次；

· 呼吸幅度監(jiān)測(cè)反應(yīng)時(shí)間呼吸率每1.7秒向用戶(hù)報(bào)告, 移動(dòng)報(bào)告的值是10次呼吸的的平均數(shù)；

血氧呼吸數(shù)據(jù)采集器

8通道數(shù)據(jù)采集器

可對(duì)1-8只老鼠進(jìn)行脈搏、血氧、呼吸的數(shù)據(jù)測(cè)量

模擬信號(hào)輸出模塊

搭配模擬信號(hào)輸出模塊實(shí)時(shí)輸出模擬心博

多鐘測(cè)試探頭可選

根據(jù)需要可選擇老鼠清醒狀態(tài)下使用的頸部探頭麻醉狀態(tài)下使用的足部探頭和大腿探頭

測(cè)量軟件

實(shí)時(shí)顯示監(jiān)測(cè)數(shù)據(jù)具有診斷模式具備報(bào)價(jià)功能數(shù)據(jù)可儲(chǔ)存為T(mén)ext貨Windaq格式

設(shè)備正在對(duì)清醒活動(dòng)狀態(tài)的大鼠進(jìn)行長(zhǎng)時(shí)間、持續(xù)的數(shù)據(jù)采集

玉研儀器是美國(guó)STARR公司的中國(guó)代理美國(guó)Starr公司的Mouseox是專(zhuān)門(mén)應(yīng)用于小鼠和大鼠的監(jiān)護(hù)儀可以測(cè)量脈搏血氧呼吸心率脈搏幅度呼吸幅度體溫等參數(shù)。詳情請(qǐng)!

· Calibration and Validation of the MouseOx® Small-Animal Pulse Oximeter
Kingman P. Strohl* MD, David Baekey* PhD, Susan Dase** MS and Bernie Hete** PhD.
*Department of Pulmonary and Critical Care Medicine, Case Western Reserve University
**Department of Engineering, STARR Life Sciences Corp.

· Transfusion-related Acute Lung Injury
Chelsea A. Sheppard, MDa, Lennart E. Lo¨ gdberg, MD, PhDa, James C. Zimring, MD, PhDa, Christopher D. Hillyer, MDb,
aDepartment of Pathology and Laboratory Medicine, Room D-655, Emory University School of Medicine, 1364 Clifton Road, NE, Atlanta, GA 30322, USA
bDepartment of Pathology and Laboratory Medicine, Transfusion Medicine Program, Room D-655, Emory University Hospital, 1364 Clifton Road, NE, Atlanta, GA 30322, USAHEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA

· Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
Adam T. Boutin,1 Alexander Weidemann,1 Zhenxing Fu,5 Lernik Mesropian,1
Katarina Gradin,2 Colin Jamora,1 Michael Wiesener,3 Kai-Uwe Eckardt,3 Cameron J. Koch,4 Lesley G. Ellies,5
Gabriel Haddad,5 Volker H. Haase,4 M. Celeste Simon,4 Lorenz Poellinger,2 Frank L. Powell,5 ａnd Randall S. Johnson1
1Molecular Biology Section, Division of Biological Sciences, UC San Diego, La Jolla, CA 92093, USA
2Karolinska Institute, Stockholm S-17177, Sweden
3University of Erlangen, Erlangen D-91054, Germany
4University of Pennsylvania Medical School, Philadelphia, PA 19104, USA
5Departments of Medicine, Pediatrics, and Pathology, UC San Diego School of Medicine, La Jolla 92093 CA, USA

· Age-related cardiac muscle sarcopeniaCombining experimental
and mathematical modeling to identify mechanisms
Jing Lin a,b, Elizabeth F. Lopez a,c, Yufang Jin f, Holly Van Remmen d,e, Terry Bauch a, Hai-Chao Han g, Merry L. Lindsey a,b,d,e
aDivision of Cardiology, Department of Medicine, The University of Texas Health Science Center at San Antonio (UTHSCSA),
7703 Floyd Curl Dr., MC-7872, San Antonio, TX 78229, USA
bThe Janey Briscoe Center of Excellence in Cardiovascular Research, UTHSCSA, USA
cJohn Jay Science and Engineering Academy, UTHSCSA, USA
dThe Barshop Institute for Longevity and Aging Studies, UTHSCSA, USA
eDepartment of Cellular and Structural Biology, UTHSCSA, USA
fDepartment of Electrical Engineering, UTSA, USA
gDepartment of Mechanical Engineering, UTSA, USA

· Post infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection
Ian C. Davis1, Eduardo R. Lazarowski2, Fu-Ping Chen3, Judy M. Hickman-Davis1, Wayne M. Sullender3,4, and Sadis Matalon1,4,5
1 Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
2 Department of Medicine, UNC, Chapel Hill, NC, USA
3 Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
4 Department of Micrology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
5 Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL 35233, USA

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